Phase I Trial of huA33 Plus Chemotherapy in Patients With Metastatic Colorectal Cancer

Oxaliplatin was administered at 85 mg/m2 on day 2 of every 2 week regimen.

The dose of 5-FU was 400 mg/m2 IV bolus followed by continuous IV infusion at 600 mg/m2 over 22 hours on day 2 and day 3 of every 2 week regimen.

Leucovorin was administered at a dose of 200mg/m2 on day 2 and day 3 of every 2 week regimen.

huA33 was administered intravenously over a period of 30 minutes once a week at a dose of 10 mg/m2.