Safety and Effectiveness of D-Cycloserine in Children With Autism

PHASE3CompletedINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

February 29, 2004

Primary Completion Date

September 30, 2007

Study Completion Date

August 31, 2010

Conditions
Autistic Disorder
Interventions
DRUG

D-cycloserine

D-Cycloserine 0.6mg/kg/day in week 1 D-Cycloserine 1.1mg/kg/day in week 2 D-Cycloserine 1.7mg/kg/day in week 3-8 Flexible dosing based on response. Capsule Strength: 10mg, 20mg

DRUG

Placebo

Placebo: same dosing schedule and capsule strength

Trial Locations (1)

46202

Riley Hospital for Children, Christian Sarkine Autism Treatment Center, Indianapolis

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

collaborator

National Alliance for Research on Schizophrenia and Depression

OTHER

collaborator

Indiana University School of Medicine

OTHER

lead

Indiana University

OTHER

NCT00198120 - Safety and Effectiveness of D-Cycloserine in Children With Autism | Biotech Hunter | Biotech Hunter