A Study of Sertraline to Prevent PTSD

PHASE4CompletedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

November 30, 2002

Primary Completion Date

July 31, 2006

Study Completion Date

July 31, 2006

Conditions
Posttraumatic Stress DisorderDepression
Interventions
DRUG

Placebo

The placebo was administered for 24 weeks on a flexible fixed schedule beginning at 25mg per day, and increasing as high as 150 mg/day. Both groups received the assigned medication and dose over a 24-week period. At Week 12, the placebo was tapered at a rate of 25mg every 3 days until it was discontinued.

DRUG

Sertraline

The drugs were administered for 24 weeks on a flexible fixed schedule beginning at 25mg per day, and increasing as high as 150 mg/day. Both groups received the assigned medication and dose over a 24-week period. At Week 12, the medication was tapered at a rate of 25mg every 3 days until it was discontinued.

Trial Locations (1)

02114

Massachusetts General Hospital, Boston

All Listed Sponsors
lead

Massachusetts General Hospital

OTHER

NCT00182078 - A Study of Sertraline to Prevent PTSD | Biotech Hunter | Biotech Hunter