24
Participants
Start Date
January 31, 2005
Primary Completion Date
October 31, 2008
Study Completion Date
July 31, 2016
Recombinant Human DNase (Pulmozyme)
2.5 mg in 3 ml diluent delivered by nebulization given daily for 6 months with 3 ml diluent placebo delivered by nebulization given daily for 6 months
Placebos
2.5 ml sterile solution (8.77 mg/ml sodium chloride, 0.15 mg/ml calcium chloride, pH 7.0 +/- 2.0) delivered daily by nebulization for 6 months, either preceding or following 6 months of Pulmozyme depending on randomization of the subject
Nationwide Children's Hospital, Columbus
Collaborators (1)
Genentech, Inc.
INDUSTRY
Nationwide Children's Hospital
OTHER