TRIGR - Primary Prevention Study for Type 1 Diabetes in Children at Risk

NACompletedINTERVENTIONAL
Enrollment

5,156

Participants

Timeline

Start Date

May 6, 2002

Primary Completion Date

March 31, 2017

Study Completion Date

September 30, 2017

Conditions
Diabetes Mellitus, Type 1
Interventions
DIETARY_SUPPLEMENT

Hydrolysed infant formula

Participants in the Hydrolysed infant formula -group received the test formula, casein hydrolysate (Nutramigen™, Mead Johnson Nutritionals), not containing antigenic CM protein, whenever breast milk is not available.

DIETARY_SUPPLEMENT

Nonhydrolysed infant formula

Participants in the Nonydrolysed infant formula -group received the CM protein containing control formula which has an addition (20 %) of Nutramigen, whenever breast milk is not available.

Trial Locations (18)

10

3rd Faculty of Medicine, Charles University, University Hospital Vinohrady, Prague

1083

Semmelweis Medical University, Budapest

1210

Centre Hospitalier de Luxembourg, Luxembourg

2145

Children's Hospital at Westmead, Westmead

28040

Hospital Clinico San Carlos, Madrid

30173

Kinderkrankenhaus auf der Bult, Hanover

33620

The University of South Florida, Tampa

48903

Hospital de Cruces, Barakaldo

51014

Tartu University Children's Hospital, Tartu

15213-2583

University of Pittsburgh, Pittsburgh

N6A 5K8

Robarts Research Institute, London

00029HUS

University of Helsinki, Helsinki

09134

St. Michele Hospital, Cagliari

00155

University Campus Bio-Medico of Rome, Rome

3015 GJ

Sophia Children's Hospital, Rotterdam

50-376

Medical University of Wroclaw, Wroclaw

S-58185

University of Linkoping, Linköping

CH-8032

University Children's Hospital, Zurich

All Listed Sponsors
collaborator

United States Congress

FED

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

collaborator

Juvenile Diabetes Research Foundation

OTHER

collaborator

European Community (EC)

OTHER_GOV

collaborator

European Foundation for the Study of Diabetes

OTHER

collaborator

Mead Johnson Nutrition

INDUSTRY

collaborator

Academy of Finland

OTHER

collaborator

Diabetes Research Foundation, Finland

OTHER

collaborator

Dutch Diabetes Research Foundation

OTHER

lead

University of Helsinki

OTHER