The Autonomic Nervous System and Obesity

PHASE1CompletedINTERVENTIONAL
Enrollment

128

Participants

Timeline

Start Date

April 30, 2003

Primary Completion Date

January 31, 2017

Study Completion Date

January 31, 2017

Conditions
OBESITYHYPERTENSIONPURE AUTONOMIC FAILURESHY-DRAGER SYNDROME
Interventions
DRUG

Trimethaphan

Start dose: 0.05 ml/min (0.5 mg/min), IV infusion. The dose will be increased every 2-4 minutes to 1, 2, 4, and 5 mg/min. Total duration: 1 hour

DRUG

Trimethaphan

Start dose: 0.05 ml/min (0.5 mg/min), IV infusion. The dose will be increased every 30 minutes to 1, 2, 4, and 5 mg/min. Total duration: 1-2 hours

DRUG

Pseudoephedrine

30mg tablet,VO. Single dose.

Trial Locations (1)

37232

Vanderbilt University, Nashville

All Listed Sponsors
lead

Vanderbilt University

OTHER

NCT00179023 - The Autonomic Nervous System and Obesity | Biotech Hunter | Biotech Hunter