42
Participants
Start Date
October 31, 2002
Primary Completion Date
April 30, 2013
Study Completion Date
April 30, 2013
sertraline
Patients will be assigned by random selection to sertraline (50mg daily for one week, then 100mg daily) or bupropion (SR formulation, 150 mg daily for 1 week, then 150 mg BID). A second CSF collection will be completed after 4 weeks of the sertraline treatment (during week 5).
bupropion
Patients will be assigned by random selection to sertraline (50mg daily for one week, then 100mg daily) or bupropion (SR formulation, 150 mg daily for 1 week, then 150 mg BID). A second CSF collection will be completed after 4 weeks of the sertraline treatment (during week 5).
Vanderbilt University Medical Center, Nashville
Vanderbilt University Medical Center
OTHER