125
Participants
Start Date
September 30, 2003
Primary Completion Date
October 31, 2007
Study Completion Date
October 31, 2007
Valsartan 320 mg
Patients received 160 mg valsartan for 4 weeks. Patients were then up-titrated to receive either 320 mg valsartan for the following 8 weeks.
Amlodipine 10 mg
Patients received 5 mg amlodipine for four weeks. Patients were then up-titrated to receive 10 mg amlodipine for the following 8 weeks.
Hydrochlorothiazide
At Week 12, patients who did not meet target Blood Pressure for both Systolic Blood Pressure \< 140 mmHg and Diastolic Blood Pressure \< 90 mmHg were eligible to receive 12.5 mg open-label Hydrochlorothiazide for the following 26 weeks.
Novartis Pharmaceuticals, Basel
Lead Sponsor
Novartis
INDUSTRY