844
Participants
Start Date
August 31, 2011
Primary Completion Date
November 30, 2014
Study Completion Date
May 31, 2015
Isoniazid
The dosage of the medication is determined according to the weight of the child. The dose is once per day, 10-15 mg/kg/day (max=300mg/day). Total duration of treatment is 9 months. Both a detailed dose chart calculating doses by weight and age and protocols for preparation of medications (crushing pills, mixing suspensions) are available.
Rifampin
The dosage of the medication is determined according to the weight of the child. The dose is once per day, 10-20 mg/kg/day (max=600mg/day). Total duration of treatment is 4 months. Both a detailed dose chart calculating doses by weight and age and protocols for preparation of medications (crushing pills, mixing suspensions) are available.
Woolcock Institute of Medical Research, Sydney
Centre de Pneumophthysiologie, Cotonou
Universidade Gama Filho, Centro de Ciências Biológicas e da Saúde, Rio de Janeiro
University of Alberta, Edmonton
British Columbia Centre for Disease Control, Vancouver
Research and Development Unit, Komfo Anokye Teaching Hospital, Kumasi
Service de Pneumo-Phtisiologie, Hopital National Ignace Deen, Conakry
Health Research Unit, Faculty of Medicine, Bandung
Montreal Children's Hospital, Montreal
Canadian Institutes of Health Research (CIHR)
OTHER_GOV
McGill University
OTHER