Study of Dasatinib in Patients With Advanced Solid Tumors

PHASE1TerminatedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

August 31, 2005

Primary Completion Date

March 31, 2007

Study Completion Date

March 31, 2007

Conditions
Tumors
Interventions
DRUG

Dasatinib + Ketoconazole

Tablets, Oral, Segment 1: escalating single dose of dasatinib starting at 140 mg q24 hours on Day 1-8; single dose of ketoconazole 200 mg q12 hours on Days 3-8; Segment 2: single daily oral doses of dasatinib, once daily, until disease progression or unacceptable toxicity.

Trial Locations (4)

33612

H. Lee Moffitt Cancer Center, Tampa

37203

Sarah Cannon Research Institute, Nashville

77030

Md Anderson Cancer Center, Houston

90404

Lee S. Rosen M.D., Santa Monica

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY

NCT00162214 - Study of Dasatinib in Patients With Advanced Solid Tumors | Biotech Hunter | Biotech Hunter