Erlotinib or Placebo Following Chemoradiotherapy (Chemo/RT) in Stage III Non-Small Cell Lung Cancer (NSCLC)

PHASE3CompletedINTERVENTIONAL
Enrollment

245

Participants

Timeline

Start Date

May 31, 2005

Primary Completion Date

April 30, 2014

Study Completion Date

April 30, 2014

Conditions
Carcinoma, Non-Small-Cell LungNon-small Cell Lung CancerNSCLC
Interventions
DRUG

Erlotinib (tarceva)

Erlotinib 150mg orally each day. Patients will be treated on a continuous, once daily oral dosing schedule until disease progression, withdrawal of consent, unacceptable adverse events, death or completion of 3 years of therapy.

DRUG

Placebo

Matched placebo orally each day. Patients will be treated on a continuous, once daily oral dosing schedule until disease progression, withdrawal of consent, unacceptable adverse events death or completion of 3 years of therapy.

Trial Locations (65)

10451

Lincoln Hospital, The Bronx

10956

Hematology Oncology Associates of Rockland, PC, New York

11365

Queens Medical Associates, Fresh Meadows

11501

Winthrop University Hospital, Mineola

20010

Washington Cancer Institute, Washington D.C.

20815

Frederick Smith, MD, Chevy Chase

20832

Community Hematology Oncology, Olney

21215

Sinai Hospital of Baltimore, Baltimore

21218

Union Memorial Hospital, Baltimore

21225

Harbor View Cancer Center, Baltimore

21237

Franklin Square Hospital Center, Baltimore

23606

Virginia Oncology Associates Research Program, Newport News

26505

Morgantown Internal Medicine Group, Morgantown

27534

Southeastern Medical Oncology Center, Goldsboro

29201

SCOA-SC Onc Assoc, Columbia

32055

Cancer Care of North Florida, Lake City

32763

Mid Florida Oncology, Orange City

32806

MD Anderson, Orlando

33321

Oncology & Hematology Association of West Broward, Tamarac

33410

Palm Beach Cancer Institute, West Palm Beach

33458

Jupiter Medical Center, Jupiter

33901

Florida Cancer Specialists, Fort Myers

33919

Lee Cancer Clinic, Fort Myers

34613

Pasco Hernando Oncology Associates, Brooksville

34652

Pasco/Hernando Oncology, New Port Richey

35235

Birmingham Hematology and Oncology Associates, LLC, Birmingham

35801

Oncology Specialties, P.C., Huntsville

41701

Kentucky Cancer Clinic, Hazard

42003

Western Hematology Oncology, Paducah

44195

The Cleveland Clinic Foundation Hematology/Med Oncology, Cleveland

44710

Aultman Cancer Center, Canton

46254

Investigative Clinical Research of Indiana LLC, Indianapolis

46904

Howard Regional Health System, Kokomo

48706

Bay Medical Cancer Center, Bay City

50010

McFarland Clinic, Ames

60007

Alexian Brothers Hospital Network, Elk Grove Village

60435

Joliet Hematology Associates, Joliet

68114

Methodist Cancer Center, Omaha

68510

Southeast Nebraska Hematology/Oncology, Lincoln

71913

Genesis Cancer Center, Hot Springs

72913

Cooper Clinic, Fort Smith

75080

Hope Oncology, Richardson

75701

Blood and Cancer Center of East Texas, Tyler

Tyler Hematology/Oncology, Tyler

77030

VA Department of Hematology/Oncology, Houston

89106

Nevada Cancer Research Foundation, Las Vegas

94704

Alta Bates Comprehensive Cancer Center, Berkeley

95816

Mercy General Hospital, Sacramento

96001

Northstate Cancer Speciality, Redding

97201

Legacy Good Samaritan, Portland

98310

Olympic Hematology/Oncology, Bremerton

06105

St. Francis Hospital Cancer Center, Hartford

06457

Connecticut Oncology Group, Middletown

06050

George Bray Cancer Center/New Britain General Hospital, New Britain

06320

Oncology and Hematology Associates, PC, New London

06856

Whittingham Cancer Center at Norwalk Hospital, Norwalk

06902

Hematology/Oncology PC/Carl and Dorothy Bennet Cancer Center, Stamford

04074

Maine Center for Cancer Medicine, Scarborough

01805

Lahey Clinic Medical Center, Burlington

01608

Fallon Clinic Hematology/ Oncology, Worcester

03431

Dartmouth-Hitchcock-Keene, Keene

03756

Norris Cotton Cancer Center, Lebanon

00000

The Center for Cancer and Hematologic Disease, Cherry Hill

07860

Sussex County Medical Associates, Newton

05009

Veterans Administration Medical Center, White River Junction

Sponsors

Collaborators (2)

All Listed Sponsors
collaborator

Sanofi

INDUSTRY

collaborator

Genentech, Inc.

INDUSTRY

lead

Dartmouth-Hitchcock Medical Center

OTHER

NCT00153803 - Erlotinib or Placebo Following Chemoradiotherapy (Chemo/RT) in Stage III Non-Small Cell Lung Cancer (NSCLC) | Biotech Hunter | Biotech Hunter