ARREST PAD (Peripheral Arterial Disease)

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

76

Participants

Timeline

Start Date

January 31, 2004

Primary Completion Date

November 30, 2010

Study Completion Date

December 31, 2011

Conditions
Arterial Occlusive DiseaseIntermittent ClaudicationInsulin Resistance
Interventions
DRUG

atorvastatin and pioglitazone

atorvastatin 80 mg orally once daily (to reduce inflammation) and pioglitazone 30 mg orally once daily (to improve insulin sensitivity)

DRUG

atorvastatin/placebo

atorvastatin 80 mg orally once daily and matching placebo orally twice daily

DRUG

pioglitazone/placebo

pioglitazone 30 mg orally once daily and matching placebo orally once daily

DRUG

placebo/placebo

placebo orally three times daily

Trial Locations (1)

02115

Brigham & Women's Hospital, Boston

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Brigham and Women's Hospital

OTHER

NCT00153166 - ARREST PAD (Peripheral Arterial Disease) | Biotech Hunter | Biotech Hunter