Safety Study of the Proteasome Inhibitor PR-171 (Carfilzomib for Injection) in Patients With Hematological Malignancies

PHASE1CompletedINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

September 30, 2005

Primary Completion Date

October 31, 2009

Study Completion Date

October 31, 2009

Conditions
Waldenstrom's MacroglobulinemiaNon-Hodgkin's LymphomaHodgkin's DiseaseMultiple Myeloma
Interventions
DRUG

Carfilzomib

Administered as an IV bolus dose

DRUG

Dexamethasone

Administered orally prior to carfilzomib

Trial Locations (5)

10021

Memorial Sloan Kettering Cancer Center, New York

Weil Medical College of Cornell University, New York

10032

Herbert Irving Comprehensive Cancer Center, Columbia University, New York

33612

H. Lee Moffitt Cancer Center and Research Institute, Tampa

90211-1850

Tower Cancer Research Foundation, Beverly Hills

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Amgen

INDUSTRY