Preoperative Herceptin/Navelbine Versus Taxotere/Carboplatin/Herceptin in HER-2 Positive Breast Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

81

Participants

Timeline

Start Date

December 31, 2003

Primary Completion Date

January 31, 2009

Study Completion Date

August 31, 2011

Conditions
Breast Cancer
Interventions
DRUG

Herceptin

One dose given followed by an MRI, then weekly injections beginning week 3 and ending week 14.

DRUG

Navelbine

Weekly injections given starting week 3 and ending week 14

DRUG

Taxotere

Given every three weeks starting week 3 and ending on week 14

DRUG

Carboplatin

Given every three weeks starting week 3 and ending on week 14

Trial Locations (4)

06520

Yale Cancer Center, New Haven

02115

Beth Israel Deaconess Medical Center, Boston

Dana-Farber Cancer Institute, Boston

Massachusetts General Hospital, Boston

All Listed Sponsors
collaborator

Dana-Farber Cancer Institute

OTHER

collaborator

Brigham and Women's Hospital

OTHER

collaborator

Massachusetts General Hospital

OTHER

collaborator

Beth Israel Deaconess Medical Center

OTHER

collaborator

Yale University

OTHER

lead

Eric Winer, MD

OTHER

NCT00148668 - Preoperative Herceptin/Navelbine Versus Taxotere/Carboplatin/Herceptin in HER-2 Positive Breast Cancer | Biotech Hunter | Biotech Hunter