326
Participants
Start Date
July 31, 2001
Primary Completion Date
June 30, 2009
Study Completion Date
May 31, 2011
Short Course Adjuvent Chemotherapy
Post operative adjuvant chemotherapy: 5FU (425mg/m2) preceded by Folinic acid (20mg/m2) delivered over 5 days for 6 monthly cycles
Long Course Adjuvant Chemotherapy
Post operative adjuvant 5FU (425mg/m2) preceded by folinic acid (20mg/m2) delivered over 5 days for 4 monthly cycles
Short Course Radiotherapy
25 Gy in 5 fractions over 5 days.
Long Course Radiotherapy
50.4 Gy delivered in 1.8 Gy fractions over 5 1/2 weeks.
Concurrent Chemotherapy
5FU 225mg/m2/day delivered IV over continous 7 day period for the duration of radiotherapy (5 1/2 weeks).
Initial Surgery
Surgery is to be performed according to the NHMRC Guidelines for the prevention, early detection and management of colorectal cancer: Elective surgery for rectal cancer
Auckland Hospital, Auckland
Liverpool Hospital, Liverpool
Prince of Wales Hospital, Randwick
Royal Prince Alfred Hospital, Camperdown
Royal North Shore Hospital, Sydney
Westmead Hospital, Wentworthville
Newcastle Mater Misericordiae Hospital, Newcastle
Macarthur Cancer Therapy Centre, Campbelltown
The Canberra Hospital, Garran
Riverina Cancer Care Centre, Wagga Wagga
Nepean Cancer Care Centre, Penrith
Peter MacCallum Cancer Centre, East Melbourne
Peter MacCallum Cancer Centre, Melbourne
Monash Medical Centre, East Bentleigh
Alfred Hospital, Prahran
Waikato Hospital, Hamilton
Andrew Love Cancer Centre, Geelong Hospital, Geelong
Murray Valley Private Hospital, Wodonga
Royal Brisbane Hospital, Herston
Mater QRI, South Brisbane
Princess Alexandra Hospital, Woolloongabba
East Coast Cancer Centre, Tugun
North Queensland Oncology Service, Townsville
Royal Adelaide Hospital, Adelaide
Royal Perth Hospital, Perth
Sir Charles Gairdner Hospital, Nedlands
Launceston General Hospital, Launceston
Wellington Hospital, Wellington
Mater Private Hospital, Brisbane
Peter MacCallum Cancer Centre, Bendigo
Box Hill Hospital, Box Hill
St Vincents Melbourne, Fitzroy
Western Hospital, Footscray
Frankston Hospital, Frankston
Australasian Gastro-Intestinal Trials Group
NETWORK
Colorectal Surgical Society of Australasia (CSSA)
UNKNOWN
Royal Australasian College of Surgeons (RACS)
UNKNOWN
Trans Tasman Radiation Oncology Group
OTHER