296
Participants
Start Date
March 2, 2000
Primary Completion Date
May 31, 2012
Study Completion Date
November 5, 2021
12 Week Stanford V Chemotherapy
12 weeks of Stanford V chemotherapy plus low-dose, involved-field RT in children
4 cycles of VAMP chemotherapy
4 cycles of VAMP chemotherapy alone in patients who achieve a complete response after 2 cycles of VAMP chemotherapy. For patients that do not achieve a complete response after 2 cycles of VAMP, they will receive low low-dose involved field radiotherapy at the end of all chemotherapy.
2 alternating cycles of VAMP/COP chemotherapy
2 alternating cycles of VAMP/COP chemotherapy (total 4 cycles of chemotherapy) plus low-dose, involved-field RT.
3 alternating cycles of VAMP/COP chemotherapy
3 alternating cycles of VAMP/COP chemotherapy (total 6 cycles of chemotherapy) plus low-dose, involved-field RT
St. Jude Children's Research Hospital, Memphis
Stanford University, Palo Alto
Maine Children's Cancer Program, Portland
Dana Farber Cancer Institute, Boston
Massachusetts General Hospital, Boston
St. Jude Children's Research Hospital
OTHER