A Safety and Tolerability Evaluation of Two 10-Week Dose Regimens of Orally-Administered PF-04494700 in Alzheimer's Patients

PHASE2CompletedINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

October 31, 2005

Primary Completion Date

June 30, 2006

Study Completion Date

June 30, 2006

Conditions
Alzheimer Disease
Interventions
DRUG

PF-04494700 - Low Dose Arm

30 mg loading dose for 6 days, followed by 10 mg daily

DRUG

PF-04494700 - High Dose Arm

60 mg loading dose for 6 days, followed by 20 mg daily

DRUG

Placebo Comparator

Matching placebo.

Trial Locations (12)

32216

Pfizer Investigational Site, Jacksonville

32806

Pfizer Investigational Site, Orlando

33009

Pfizer Investigational Site, Hallandale

33321

Pfizer Investigational Site, Fort Lauderdale

33407

Pfizer Investigational Site, West Palm Beach

33773

Pfizer Investigational Site, Largo

33912

Pfizer Investigational Site, Fort Myers

38119

Pfizer Investigational Site, Memphis

85351

Pfizer Investigational Site, Sun City

92103

Pfizer Investigational Site, San Diego

93720

Pfizer Investigational Site, Fresno

94118

Pfizer Investigational Site, San Francisco

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Trans Tech Pharmaceuticals

UNKNOWN

lead

Pfizer

INDUSTRY