A Study Of Oral Palbociclib (PD-0332991), A Cyclin-Dependent Kinase Inhibitor, In Patients With Advanced Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

September 30, 2004

Primary Completion Date

July 31, 2008

Study Completion Date

December 31, 2014

Conditions
NeoplasmsLymphoma, Non-Hodgkin
Interventions
DRUG

PD-0332991

Dose ranging study - evaluating two oral schedule: (1) 3/1 Schedule - PD-0332991 administered days 1-21 of a 28-day schedule, doses ranging from 25 to 150 mg once daily; (2) 2/1 Schedule - PD-0332991 administered days 1-14 of a 21-days schedule, doses ranging from 100 to 225 mg once daily

Trial Locations (4)

10065

Memorial Sloan Kettering Cancer Center, New York

19104

Abramson Cancer Center Hospital of the University of Pennsylvania, Philadelphia

Pharmacy/PCAM/West Pavillion, Philadelphia

48201

Karmanos Cancer Institute, Detroit

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY