A Study of OGX-011/Gemcitabine/Platinum-Based Regimen in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC)

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

85

Participants

Timeline

Start Date

November 30, 2004

Primary Completion Date

March 31, 2010

Study Completion Date

March 31, 2010

Conditions
Non-small Cell Lung Cancer
Interventions
DRUG

custirsen sodium

Custirsen sodium (OGX-011) was to be infused intravenously over 2 hours on Days -7, -5, and 3 of Cycle 1 (pretreatment loading dose). OGX 011 was then to be infused for 2 hours weekly on Days 1, 8, and 15 of a 21-day cycle. Gemcitabine (GEM) was to be infused intravenously for 30 minutes on Days 1 and 8 and either cisplatin (CIS) or carboplatin (CARBO) were to be infused intravenously on Day 1 of this 21-day cycle. Patients were to receive a maximum of 6 cycles (1 cycle = 21 days)

Trial Locations (15)

12208

New York Oncology Hematology, Albany

29605

Cancer Centers of the Carolinas, Greenville

75246

Mary Crowley Medical Research Center, Dallas

90033

LAC-USC Medical Center, Los Angeles

University of Southern California Norris, Los Angeles

97239

Oregon Health and Science University, Portland

Unknown

Tom Baker Cancer Centre, Calgary

BC Cancer Agency, Fraser Valley Centre, Surrey

BC Cancer Agency, Vancouver Center, Vancouver

Dr. H. Bliss Murphy Cancer Center, St. John's

Royal Victoria Hospital of Barrie, Barrie

London Regional Cancer Centre, London

Ottawa Hospital, Ottawa

Toronto Sunnybrook Regional Cancer Center, Toronto

Hopital Laval, Ste-Foy

Sponsors
All Listed Sponsors
lead

Achieve Life Sciences

INDUSTRY