Bevacizumab in Combination With Temozolomide in Patients With Neuroendocrine Tumors

PHASE2CompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

November 30, 2004

Primary Completion Date

July 31, 2005

Study Completion Date

December 31, 2012

Conditions
Neuroendocrine Tumors
Interventions
DRUG

Bevacizumab

Given intravenously every other week. Participants can continue to receive study drug as long as there is no disease progression or serious side effects.

DRUG

Temozolomide

Given once daily for one week followed by a one week rest period. This one-week on/one-week off scheduled will be continued as long as there is no disease progression or serious side effects.

Trial Locations (3)

02115

Beth Israel Deaconess Medical Center, Boston

Dana-Farber Cancer Insitute, Boston

Massachusetts General Hospital, Boston

Sponsors
All Listed Sponsors
collaborator

Massachusetts General Hospital

OTHER

collaborator

Beth Israel Deaconess Medical Center

OTHER

collaborator

Brigham and Women's Hospital

OTHER

collaborator

Genentech, Inc.

INDUSTRY

collaborator

Schering-Plough

INDUSTRY

lead

Dana-Farber Cancer Institute

OTHER