Escitalopram for the Prevention of PEGASYS-associated Depression in Hepatitis C Virus-infected Patients

PHASE3CompletedINTERVENTIONAL
Enrollment

208

Participants

Timeline

Start Date

January 31, 2004

Primary Completion Date

September 30, 2008

Study Completion Date

September 30, 2008

Conditions
Depression
Interventions
DRUG

Escitalopram

DRUG

Placebo

DRUG

Peginterferon alfa-2a

Patients with HCV genotype 1 or 4 received treatment for 48 weeks with PEGinterferon-alfa2a, 180 mcg weekly. Patients with genotype 2 or 3 received PEGinterferon-alfa2a, 180 mcg weekly.

DRUG

Ribavirin

Patients with HCV genotype 1 or 4 received treatment for 48 weeks with ribavirin, 1000 mg per day (body weight 75 kg) or 1200 mg per day (body weight, 75 kg). Patients with HCV genotype 2 or 3 received ribavirin, 800 mg per day for 24 weeks.

Trial Locations (1)

04103

Department of Gastroenterolgy and Rheumatology, Sektion Hepatology, Leipzig

All Listed Sponsors
lead

Charite University, Berlin, Germany

OTHER

NCT00136318 - Escitalopram for the Prevention of PEGASYS-associated Depression in Hepatitis C Virus-infected Patients | Biotech Hunter | Biotech Hunter