10,154
Participants
Start Date
June 30, 2003
Primary Completion Date
October 31, 2008
Study Completion Date
January 31, 2009
Dietary Supplement/Vitamins
Vitamin C (1000 mg) and Vitamin E (400 IU) per capsule, two capsules daily between randomization (at 9 - 16 weeks gestation) up to delivery.
Placebo for Vitamin C and Vitamin E
Placebo two capsules daily between randomization (at 9 - 16 weeks gestation) up to delivery.
Columbia University, New York
University of Pittsburgh Magee Womens Hospital, Pittsburgh
Drexel University, Philadelphia
Wake Forest University School of Medicine, Winston-Salem
University of North Carolina - Chapel Hill, Chapel Hill
University of Alabama - Birmingham, Birmingham
Ohio State University, Columbus
Case Western University, Cleveland
Wayne State University, Detroit
Northwestern University, Chicago
University of Texas - Southwest, Dallas
University of Texas - Houston, Houston
University of Texas Medical Branch, Galveston
University of Utah Medical Center, Salt Lake City
Oregon Health and Sciences University, Portland
Brown University, Providence
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
The George Washington University Biostatistics Center
OTHER