NCT00131664 - Avandia™ + Amaryl™ or Avandamet™ Compared With Metformin (AVALANCHE™ Study) | Biotech Hunter

Enrollment

391

Participants

Timeline

Start Date

September 30, 2005

Primary Completion Date

January 31, 2008

Study Completion Date

January 31, 2008

Conditions

Type 2 Diabetes Mellitus

Interventions

DRUG

Avandamet

Avandamet 2 / 500 mg twice daily titration up to 4 mg / 1000 mg twice daily compared to Avandia 4 mg and Amaryl 1 mg once daily over 6 months or compared to Metformin 500 mg twice daily up to 1000 mg over 6 months.

DRUG

Avandia and Amaryl

Avandia 4 mg and Amaryl 1 mg once daily compared to Avandamet 2 / 500 mg twice daily titration up to 4 mg / 1000 mg twice daily, or compared to Metformin 500 mg twice daily up to 1000 mg over 6 months.

DRUG

Metformin

Metformin 500 mg twice daily up to 1000 mg over 6 months compared to Avandia 4 mg and Amaryl 1 mg once daily or compared to Avandamet 2 / 500 mg twice daily titration up to 4 mg / 1000 mg twice daily

Trial Locations (1)

m5b 2p9

Canadian Heart Research Centre, Toronto