260
Participants
Start Date
April 30, 2002
Primary Completion Date
September 30, 2009
Study Completion Date
September 30, 2009
Tuberculin, Purified Protein Derivative
A tuberculin skin test used to diagnose latent tuberculosis (TB) infection. 2 TU dose
MLSA-LAM
Mycobacterium leprae soluble antigen with minimal amounts of immunosuppressive lipoglycans; dosages 0.1 and 1.0 micrograms; administered in sterile diluent 0.9% saline (NaCl).
MLCwA
Cell wall-associated proteins of Mycobacterium leprae; dosages 0.1 and 1.0 micrograms; administered in sterile diluent 0.9% saline (NaCl).
Tuberculin, Purified Protein Derivative
Licensed TB reagent, 100 microliters, 5 TU dose.
Placebo
Saline (NaCl) serves as a diluent control in Stage A and B only.
Colorado State University - Microbiology, Immunology & Pathology, Fort Collins
Anandaban Hospital, Kathmandu
Green Pastures Hospitals, Kathmandu
Lalitpur Nursing Campus, Kathmandu
Patan Hospital, Kathmandu
Tribhuvan University - Anandaban Hospital, Kathmandu
National Institute of Allergy and Infectious Diseases (NIAID)
NIH