NCT00124072View on ClinicalTrials.gov

Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine

PHASE3CompletedINTERVENTIONAL
Enrollment

12,064

Participants

Timeline

Start Date

July 31, 1998

Primary Completion Date

May 31, 2008

Study Completion Date

May 31, 2008

Conditions
Cardiovascular Disease
Interventions
DRUG

Simvastatin 20 mg daily

Simvastatin 20 mg tablet once daily

DIETARY_SUPPLEMENT

Folic acid 2 mg + vitamin B12 1 mg daily

Folic acid 2 mg + vitamin B12 1 mg tablet once daily

DRUG

Simvastatin 80 mg daily

Simvastatin 80 mg tablet once daily

DRUG

Placebo

Placebo vitamin B12/folic acid tablet once daily

Trial Locations (1)

OX3 7LF

CTSU, Richard Doll Building, University of Oxford, Oxford

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

University of Oxford

OTHER

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