Developmental Regulation of Proteins Responsible for Transforming Drugs in the Body

CompletedOBSERVATIONAL
Enrollment

121

Participants

Timeline

Start Date

October 31, 2000

Primary Completion Date

January 31, 2010

Study Completion Date

January 31, 2010

Conditions
Healthy
Interventions
PROCEDURE

Genotyping and Phenotyping using dextromethorphan and caffeine as probes

Single doses of dextromethorphan (0.3 mg/kg)and caffeine (3.0 mg/kg) are administered and urine is collected overnight for measurement of drug and metabolites to determine drug biotransformation activity.

Trial Locations (1)

64108

Children's Mercy Hospital, Kansas City

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

Children's Mercy Hospital Kansas City

OTHER

NCT00117715 - Developmental Regulation of Proteins Responsible for Transforming Drugs in the Body | Biotech Hunter | Biotech Hunter