Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis

PHASE2CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

November 30, 2005

Primary Completion Date

February 29, 2008

Study Completion Date

February 29, 2008

Conditions

Cystic Fibrosis

Interventions

DRUG

mannitol

400mg BD for 12 weeks

DRUG

mannitol + pulmozyme

combination

DRUG

Dornase alpha

2.5mg daily for 2 weeks

Trial Locations (2)

Great Ormond Hospital for Children, London

Royal Brompton Hospital, London