Radiotherapy Versus Radiotherapy Plus Chemotherapy in Early Stage Follicular Lymphoma

PHASE3CompletedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

February 29, 2000

Primary Completion Date

August 31, 2018

Study Completion Date

August 31, 2018

Conditions
Follicular Lymphoma
Interventions
DRUG

Cyclophosphamide

1000 mg/m2 I.V. on day 1

RADIATION

Radiotherapy

The prescribed dose to the target volume will be 30 Gy. Daily fractions of 1.5-2.0 Gy will be employed.

DRUG

Vincristine

1.4 mg/m2 (maximum single dose of 2 mg) I.V. on day 1

DRUG

Prednisolone

50 mg/m2 orally daily for days 1 - 5

DRUG

Rituximab

375 mg/m2 IV Infusion day 1

Trial Locations (21)

1001

Auckland Hospital, Auckland

2031

Prince of Wales Hospital, Randwick

2145

Westmead Hospital, Wentworthville

2298

Calvary Mater Newcastle, Newcastle

2500

Illawarra Cancer Care Centre, Wollongong

2605

The Canberra Hospital, Garran

2640

Albury Base/Murray Valley Private Hospital, West Albury

3002

Peter MacCallum Cancer Centre, East Melbourne

3084

Austin Health, Heidelberg

3200

Waikato Hospital, Hamilton

3220

Andrew Love Cancer Care Centre, Geelong Hospital, Geelong

3350

St John of God Hospital, Ballarat

4101

Radiation Oncology - Mater Centre, South Brisbane

4102

Princess Alexandra Hospital, Woolloongabba

4224

Genesis Cancer Care (previously Premion), Tugun

5000

Royal Adelaide Hospital, Adelaide

5011

The Queen Elizabeth Hospital, Woodville

6009

Sir Charles Gairdner Hospital, Nedlands

7250

Launceston General Hospital, Launceston

7902

Wellington Hospital, Wellington

Unknown

Princess Margaret Hospital, Toronto

All Listed Sponsors
collaborator

Australasian Leukaemia and Lymphoma Group

OTHER

lead

Trans Tasman Radiation Oncology Group

OTHER

NCT00115700 - Radiotherapy Versus Radiotherapy Plus Chemotherapy in Early Stage Follicular Lymphoma | Biotech Hunter | Biotech Hunter