302
Participants
Start Date
September 30, 2003
Primary Completion Date
April 30, 2008
Study Completion Date
July 31, 2008
Naltrexone
100mg/day, up to 8 weeks during Phase 1, 16 weeks in phase 2.
placebo
placebo comparer for 16 weeks in phase 2.
Medication Management (MM)
Brief manual-based therapy for up to 8 weeks during phase 1, 16 during phase 2.
Combined Behavioral Intervention (CBI)
45-60 minute sessions with a certified therapist focused on resolving ambivalence and skill building. Number of sessions guided by achievement of goals identified within treatment plan; minimum 9, maximum 20 sessions over 16 weeks.
Telephone Counseling
Bi-weekly telephone calls lasting 15-20 minutes focused on the same content as MM.
University of Pennsylvania Treatment Research Center, Chestnut Street, Philadelphia
University of Pennsylvania
OTHER