212
Participants
Start Date
May 31, 2005
Primary Completion Date
April 30, 2008
Study Completion Date
April 30, 2008
Deferasirox (ICL670)
Deferasirox was provided in 125 mg, 250 mg, and 500 mg dispersible tablets and was administered orally at an initial dose of 20 mg/kg/day.
Deferoxamine (DFO)
Deferoxamine was supplied in vials of 500 mg and 2000 mg administered subcutaneously for a weekly dose of 175 mg/kg.
Weill Medical College of Cornell University, New York
Columbia University, New York
SUNY Downstate Medical Center, Brooklyn
New York Methodist Hospital, Brooklyn
Children's Hospital of Pittsburgh, Pittsburgh
Hillman Cancer Center, Pittsburgh
Pennsylvania Oncology/Hematology, Philadelphia
Jefferson University, Philadelphia
Children's National Medical Center, Washington D.C.
Howard University Hospital, Washington D.C.
Children's Hospital of the King's Daughter, Norfolk
Carolinas Medical Transplant Center, Charlotte
Santee Hematology/Oncology, Sumter
Liberty Hematology Oncology Center, Columbia
Palmetto Health Clinical Trials, Columbia
Emory University School of Medicine, Atlanta
Children's Healthcare of Atlanta at Scottish Rite, Atlanta
Backus Children's Hospital, Savannah
Miami Children's Hospital, Miami
H. Lee Muffit Cancer Center and Research Institute/James A. Haley Veterans Hospital, Tampa
University of Alabama Pediatric Hematology/Oncology, Birmingham
University of Alabama Medical center, Birmingham
University of South Alabama Medical Center, Mobile
University of South Alabama, Mobile
St. Jude's Children Research Hospital, Memphis
University of Cincinnati, Cincinnati
Pediatric Sickle Cell Program/James Whitcomb Riley Hospital for Children, Indianapolis
Karmanos Cancer Institute, Detroit
University of Illinois at Chicago, Chicago
Washington University School of Medicine, St Louis
Tulane University Sickle Cell Center, New Orleans
Children's Hospital, New Orleans
St. Jude Children's Hospital Affiliate, Baton Rouge
LSU Health Sciences Center/Carroll W. Feist Professor of Cancer Research, Shreveport
Children's Hospital Medical Center, Cincinnati
The University of Oklahoma, Oklahoma City
Scott and White Memorial Hospital & Clinics, Temple
Loma Linda University Medical Center, Loma Linda
Children's Hospital Oakland, Oakland
Center for Cancer and Blood Disorders, Washington D.C.
Tampa Children's Hospital at St Joseph's, Tampa
Tampa Children's Hospital at St. Joseph's, Tampa
Adult Sickle Cell Clinic, Augusta
Children's Memorial Hospital, Chicago
Brigham and Woman's Hospital/Harvard Medical School, Boston
Children's Hospital Boston, Boston
Children's Hospital, Boston
University of Michigan, Ann Arbor
Sickle Cell Center, Montefiore Hospital, The Bronx
Children's Hospital of Philadelphia, Philadelphia
Drexel University College of Medicine, Philadelphia
St Jude's Children's Research Hospital, Memphis
Cooks Children's Hospital, Fort Worth
Texas Children's Hospital/Baylor College of Medicine, Houston
Medical College of Virginia, Richmond
Virginia Commonwealth University, Richmond
University of Alberta, Edmonton
The Ottawa Hospital, Ottawa
Hopital Ste-Justine, Montreal
Lead Sponsor
Novartis Pharmaceuticals
INDUSTRY