NCT00108355View on ClinicalTrials.gov

Vasoconstrictors as Alternatives to Albumin After Large-Volume Paracentesis (LVP) in Cirrhosis

PHASE4CompletedINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

December 31, 2003

Primary Completion Date

August 31, 2010

Study Completion Date

August 31, 2012

Conditions
AscitesCirrhosis
Interventions
DRUG

Albumin

Intravenous Albumin at a dose of 8g/liter of ascitic fluid removed

DRUG

Intravenous Saline Infusion (Albumin placebo)

Intravenous saline Infusion (Albumin placebo)

DRUG

Midodrine

Midodrine oral tablet at 10 mg three times a day.

DRUG

Oral tablet (Midodrine placebo)

Oral tablet (Midodrine placebo) three times a day

DRUG

Octreotide LAR

Octreotide LAR 20 mg intramuscular injection every 30 days

DRUG

Saline injection (Octreotide LAR placebo)

Saline intramuscular injection 5 cc every 30 days.

PROCEDURE

Large Volume Paracentesis

Procedure to remove large amounts (more than 5 liter) of ascitic fluid via a catheter.

Trial Locations (1)

06516

VA Connecticut Health Care System (West Haven), West Haven

All Listed Sponsors
lead

US Department of Veterans Affairs

FED

NCT00108355 - Vasoconstrictors as Alternatives to Albumin After Large-Volume Paracentesis (LVP) in Cirrhosis | Biotech Hunter | Biotech Hunter