Optimizing the Effectiveness of Selective Serotonin Reuptake Inhibitors (SSRIs) in Treatment-Resistant Depression

PHASE2CompletedINTERVENTIONAL
Enrollment

73

Participants

Timeline

Start Date

May 31, 2004

Primary Completion Date

February 28, 2009

Study Completion Date

February 28, 2009

Conditions
Depression
Interventions
DRUG

S-adenosyl methione (SAMe)

Oral SAMe tosylate, up to 1600 mg per day for 6 weeks

DRUG

Placebo

Placebo to be taken daily for 6 weeks

Trial Locations (1)

02114

Massachusetts General Hospital, Boston

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Massachusetts General Hospital

OTHER

NCT00093847 - Optimizing the Effectiveness of Selective Serotonin Reuptake Inhibitors (SSRIs) in Treatment-Resistant Depression | Biotech Hunter | Biotech Hunter