REPEAT Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Therapy in Combination With COPEGUS (Ribavirin) in Patients With Chronic Hepatitis C (CHC) Who Did Not Respond to Previous PegIntron (Peginterferon Alfa-2b (12KD))/Ribavirin Combination Therapy

PHASE4CompletedINTERVENTIONAL
Enrollment

948

Participants

Timeline

Start Date

September 30, 2003

Primary Completion Date

May 31, 2008

Study Completion Date

May 31, 2008

Conditions
Hepatitis C, Chronic
Interventions
DRUG

Ribavirin

1000/1200mg po daily for 72 weeks

DRUG

Ribavirin

1000/1200mg po daily for 48 weeks

DRUG

peginterferon alfa-2a [Pegasys]

360 micrograms sc weekly for 12 weeks, followed by 180 micrograms sc weekly for 60 weeks

DRUG

peginterferon alfa-2a [Pegasys]

360 micrograms sc weekly for 12 weeks, followed by 180 micrograms sc weekly for 36 weeks.

DRUG

peginterferon alfa-2a [Pegasys]

180 micrograms sc weekly for 72 weeks

DRUG

peginterferon alfa-2a [Pegasys]

180 micrograms sc weekly for 48 weeks

Trial Locations (104)

1200

Brussels

3000

Leuven

8091

Zurich

9000

Ghent

10126

Torino

10552

Athens

11527

Athens

13353

Berlin

13385

Marseille

14186

Huddinge

14221

Williamsville

18003

Granada

19104

Philadelphia

20122

Milan

20246

Hamburg

21224

Baltimore

22185

Lund

23249

Richmond

24105

Kiel

28007

Madrid

28035

Madrid

28046

Madrid

29010

Málaga

30308

Atlanta

30309

Atlanta

30625

Hanover

31059

Toulouse

31404

Savannah

32256

Jacksonville

33021

Hollywood

33604

Pessac

34125

Kassel

34243

Bradenton

34295

Montpellier

34390

Istanbul

35100

Izmir

35128

Padua

36693

Mobile

37211

Nashville

38120

Memphis

39008

Santander

40138

Bologna

40225

Düsseldorf

40237

Düsseldorf

41014

Seville

41685

Gothenburg

44791

Bochum

46014

Valencia

46145

Oberhausen

50312

Des Moines

50937

Cologne

53127

Bonn

55101

Mainz

55905

Rochester

59037

Lille

60596

Frankfurt am Main

60611

Chicago

60612

Chicago

63110

St Louis

64131

Kansas City

66424

Homburg/saar

68100

Alexandroupoli

69120

Heidelberg

69288

Lyon

70100

Bari

75651

Paris

77054

Houston

78758

Austin

79106

Freiburg im Breisgau

81190

Istanbul

81377

München

84121

Salt Lake City

85259

Scottsdale

87131

Albuquerque

90033

Los Angeles

90127

Palermo

91054

Erlangen

91105

Pasadena

92118

Clichy

92123

San Diego

94010

Créteil

95482

Ukiah

97080

Würzburg

06030

Farmington

02114

Boston

02215

Boston

55404-4565

Minneapolis

Unknown

Florham Park

17604-3200

Lancaster

02920

Cranston

05401

Burlington

20270-901

Rio de Janeiro

V5Z 1H2

Vancouver

M5G 1X5

Toronto

M6H 3M1

Toronto

546 42

Thessaloniki

00133

Roma

3000-075

Coimbra

1150-314

Lisbon

1649-035

Lisbon

03010

Alicante

08036

Barcelona

06100

Ankara

B15 2TH

Birmingham

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT00087646 - REPEAT Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Therapy in Combination With COPEGUS (Ribavirin) in Patients With Chronic Hepatitis C (CHC) Who Did Not Respond to Previous PegIntron (Peginterferon Alfa-2b (12KD))/Ribavirin Combination Therapy | Biotech Hunter | Biotech Hunter