Study Evaluating the Addition of Amifostine (Ethyol®) to Idarubicin and Cytosine Arabinoside in Older Patients With Acute Myeloid Leukemia

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

July 31, 2004

Primary Completion Date

December 31, 2005

Study Completion Date

February 28, 2006

Conditions
LeukemiaAcute Myeloid Leukemia
Interventions
DRUG

Idarubincin and Amufostine (Ethyol)

Starting doses of Idarubincin(12,18 mg/m2 to 21 mg/m2), ara-C, plus amofostine (N-36)

DRUG

Idarubincin

Idarubincin (12mg/m2) and ara-C(N-18)

Trial Locations (19)

14263

Roswell Park Cancer Institute, Buffalo

19107

Thomas Jefferson University Medical College, Philadelphia

31096

Rambam Medical Center, Haifa

38120

Baptist Clinical Research Center, Memphis

47150

Cancer Care Center, New Albany

48202

Henry Ford Health System, Detroit

48236

Great Lakes Cancer Center Management Specialties, Grosse Point Woods

Cancer Management Specialists (No longer Recruiting), Grosse Pointe Woods

49100

Rabin Medical Center, Petah Tikva

49503

Spectrum Health Hospitals-Cook Research Dept. (No longer recruiting), Grand Rapids

52620

Sheba Medical Center, Tel Hasomer

53226

Medical College of Wisconsin, Milwaukee

60612

Rush University Medical Center, Chicago

66160

University of Kansas Medical Center, Kansas City

76100

Kaplan Med. Center, Rehovot

92121

Scripps Cancer Center, San Diego

07112

St. Barnabas Health Care Center, Newark

27157-1082

Wake Forest University School of Medicine, Winston-Salem

44195-001

Cleveland Clinic Foundation-Hemoatology/Oncology, Cleveland

Sponsors

Lead Sponsor

All Listed Sponsors
lead

MedImmune LLC

INDUSTRY