N2001-03: CEP-701 in Treating Young Patients With Recurrent or Refractory High-Risk Neuroblastoma

PHASE1CompletedINTERVENTIONAL
Enrollment

47

Participants

Timeline

Start Date

August 31, 2003

Primary Completion Date

September 30, 2009

Study Completion Date

February 28, 2011

Conditions
Neuroblastoma
Interventions
DRUG

lestaurtinib

Given orally twice daily x 5 consecutive days followed by a two day rest. 28 days = 1 treatment course. Courses repeated indefinitely without gap provided patient has recovered course from toxicities and no DLTs. Dose level assigned according to the planned dose escalation schedule.

Trial Locations (12)

10032

Morgan Stanley Children's Hospital of New York-Presbyterian, New York

30322

AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus, Atlanta

48109

University of Michigan Comprehensive Cancer Center, Ann Arbor

60637

University of Chicago Comer Children's Hospital, Chicago

94143

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco

94305

Lucille Salter Packer Children's Hospital, Stanford University, Palo Alto

98105

Children's Hospital and Regional Medical Center - Seattle, Seattle

90027-0700

Childrens Hospital Los Angeles, Los Angeles

02115

Children's Hospital Boston, Boston

45229-3039

Cincinnati Children's Hospital Medical Center, Cincinnati

19104-4318

Children's Hospital of Philadelphia, Philadelphia

M5G 1X8

Hospital for Sick Children, Toronto

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

New Approaches to Neuroblastoma Therapy Consortium

OTHER

NCT00084422 - N2001-03: CEP-701 in Treating Young Patients With Recurrent or Refractory High-Risk Neuroblastoma | Biotech Hunter | Biotech Hunter