30
Participants
Start Date
May 31, 2004
Primary Completion Date
March 31, 2010
Study Completion Date
October 31, 2014
Alteplase (Activase, Genentech)
Dose of Alteplase will not exceed 10 mg/d/leg and is delivered in a concentration of 100ug/mL. The actual dose delivered is based upon the length of the thrombosed vein and 1 mL is injected directly into each centimeter of a thrombosed vein in a lower extremity. The treatment will be repeated up to 4 times over a 4 day period.
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda
National Institutes of Health Clinical Center (CC)
NIH
Richard Chang, M.D.
NIH