G-CSF and AMD3100 to Mobilize Stem Cells in Healthy Volunteers

PHASE2CompletedINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

June 18, 2004

Primary Completion Date

October 25, 2012

Study Completion Date

October 25, 2012

Conditions
Healthy
Interventions
DRUG

AMD 3100 (Mozobil plerixafor)

Participants received subcutaneous injection of granulocyte colony-stimulating factor (G-CSF) at 10 mcg/kg/day for 5 days followed by a single subcutaneous injection of AMD3100 (240 mcg/kg) given 12 hours prior to apheresis peripheral blood stem cell collection. Peripheral blood stem cell collection performed on the fifth day of G-CSF administration.

DRUG

Granulocyte colony-stimulating factor (G-CSF)

Participants received subcutaneous injection of granulocyte colony-stimulating factor (G-CSF) at 10 mcg/kg/day for 5 days followed by a single subcutaneous injection of AMD3100 (240 mcg/kg) given 12 hours prior to apheresis peripheral blood stem cell collection. Peripheral blood stem cell collection performed on the fifth day of G-CSF administration.

Trial Locations (1)

20892

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda

All Listed Sponsors
lead

National Heart, Lung, and Blood Institute (NHLBI)

NIH

NCT00082329 - G-CSF and AMD3100 to Mobilize Stem Cells in Healthy Volunteers | Biotech Hunter | Biotech Hunter