699
Participants
Start Date
May 31, 2004
Primary Completion Date
February 28, 2011
Study Completion Date
February 28, 2014
Metformin
capsule, 1000 mg bid
Rosiglitazone
capsule, 4 mg bid
Lifestyle Program
a lifestyle change (LC) phase of weekly sessions for months 1-6, followed by a bi-weekly lifestyle maintenance (LM) phase through months 7-12, and a continued contact (CC) phase from months 13 through the end of the study. The CC phase sessions are scheduled monthly for the initial 12 months (study months 13-24) and then quarterly or 4 times a year to the end of the study
Columbia University Medical Center, New York
State University of New York Upstate Medical University, Syracuse
Children's Hospital of Pittsburgh, Pittsburgh
Children's Hospital of Philadelphia, Philadelphia
George Washington University Biostatistics Center, Rockville
Case Western Reserve, Cleveland
Saint Louis University Health Sciences Center, St Louis
Washington University Department of Pediatrics, St Louis
Baylor College of Medicine, Houston
University of Texas Health Science Center at San Antonio, San Antonio
University of Colorado Health Sciences Center, The Children's Hospital, Denver
Children's Hospital Los Angeles, Los Angeles
University of Oklahoma, Oklahoma City
Yale University, New Haven
Massachusetts General Hospital Diabetes Center, Boston
Joslin Diabetes Center, Boston
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH