NCT00080444 - Study of Aprepitant (MK-0869) for Chemotherapy-Induced Nausea and Vomiting (CINV) in Adolescent Participants (MK-0869-097) | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

April 30, 2004

Primary Completion Date

September 30, 2006

Study Completion Date

March 31, 2007

Conditions

Vomiting

Interventions

DRUG

aprepitant

aprepitant capsules

DRUG

ondansetron

ondansetron IV preparation

DRUG

dexamethasone

dexamethasone tablets

DRUG

placebo to aprepitant

Matching placebo to aprepitant capsules

DRUG

placebo to dexamethasone

Matching placebo to dexamethasone tablets

DRUG

rescue medication

Participants are allowed to take rescue medication throughout for nausea or vomiting. At the discretion of the investigator, participants are provided with a prescription for rescue medications. Recommended rescue medications are: 5-HT3 antagonists, phenothiazines, butyrophenones, benzamides, corticosteroids, benzodiazepines, domperidone, H1-receptor antagonist, and piperazine derivatives.

All Listed Sponsors

lead

Merck Sharp & Dohme LLC

INDUSTRY