NCT00078715View on ClinicalTrials.gov

Rapid Antidepressant Effects of Yohimbine in Major Depression

PHASE2CompletedINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

March 31, 2004

Primary Completion Date

August 31, 2009

Study Completion Date

August 31, 2009

Conditions
Depression, InvolutionalMajor Depresssion
Interventions
DRUG

Yohimbine hydrochloride

Participants receive yohimbine 0.125 mg/kg administered over 3 minutes during REM sleep.

DRUG

Placebo

Participants receive an inactive equivalent of yohimbine 0.125 mg/kg administered over 3 minutes during REM sleep.

Trial Locations (1)

20892

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda

All Listed Sponsors
lead

National Institute of Mental Health (NIMH)

NIH

NCT00078715 - Rapid Antidepressant Effects of Yohimbine in Major Depression | Biotech Hunter | Biotech Hunter