26
Participants
Start Date
April 30, 2004
Primary Completion Date
July 31, 2010
Study Completion Date
June 30, 2011
CMV CTL infusion
Three dose levels will be explored. The lowest dose level will be 1x10\^7cells/m2 and the highest will be 1x10\^8/m2. 3-6 pts will be entered at each dose level (depending on toxicity). If there are no toxicities and immunological efficacy is not seen at any dose, then the doses will be further escalated after additional local and federal approval. Additional patients will be treated at dose level 1 in order to assess the secondary objective of virus-specific immunity from the CTL infusions
Houston Methodist Hospital, Houston
Texas Children's Hospital, Houston
Center for Cell and Gene Therapy, Baylor College of Medicine
OTHER
The Methodist Hospital Research Institute
OTHER
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Baylor College of Medicine
OTHER