Induction Chemotherapy Using Cyclophosphamide and Topotecan in Treating Patients Who Are Undergoing Autologous Peripheral Stem Cell Transplantation for Newly Diagnosed or Progressive Neuroblastoma

PHASE1CompletedINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

March 31, 2004

Primary Completion Date

September 30, 2006

Study Completion Date

December 31, 2013

Conditions
Neuroblastoma
Interventions
BIOLOGICAL

filgrastim

DRUG

cisplatin

DRUG

cyclophosphamide

DRUG

doxorubicin hydrochloride

DRUG

etoposide

DRUG

isotretinoin

DRUG

melphalan

DRUG

topotecan hydrochloride

DRUG

vincristine sulfate

PROCEDURE

conventional surgery

PROCEDURE

peripheral blood stem cell transplantation

RADIATION

radiation therapy

Trial Locations (6)

2145

Westmead Hospital, Westmead

38105

St. Jude Children's Research Hospital, Memphis

60614

Children's Memorial Hospital - Chicago, Chicago

98105

Children's Hospital and Regional Medical Center - Seattle, Seattle

98405

Mary Bridge Children's Hospital and Health Center - Tacoma, Tacoma

94143-0106

UCSF Comprehensive Cancer Center, San Francisco

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK

NCT00070200 - Induction Chemotherapy Using Cyclophosphamide and Topotecan in Treating Patients Who Are Undergoing Autologous Peripheral Stem Cell Transplantation for Newly Diagnosed or Progressive Neuroblastoma | Biotech Hunter | Biotech Hunter