Immunotherapy Using Cyclosporine, Interferon Gamma, and Interleukin-2 After High-Dose Myeloablative Chemotherapy With Autologous Stem Cell Transplantation in Treating Patients With Refractory or Relapsed Hodgkin's Lymphoma

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

November 30, 2003

Primary Completion Date

June 30, 2005

Conditions
Lymphoma
Interventions
BIOLOGICAL

aldesleukin

Given IV

BIOLOGICAL

filgrastim

Given IV

BIOLOGICAL

recombinant interferon gamma

Given IV

DRUG

carmustine

Given IV

DRUG

cyclosporine

Given IV

DRUG

cytarabine

Given IV

DRUG

etoposide

Given IV

DRUG

melphalan

Given IV

PROCEDURE

autologous bone marrow transplantation

PROCEDURE

bone marrow ablation with stem cell support

PROCEDURE

peripheral blood stem cell transplantation

Trial Locations (63)

6001

Princess Margaret Hospital for Children, Perth

10029

Mount Sinai Medical Center, New York

10595

New York Medical College, Valhalla

13210

SUNY Upstate Medical University Hospital, Syracuse

15213

Children's Hospital of Pittsburgh, Pittsburgh

19899

Alfred I. duPont Hospital for Children, Wilmington

29425

Hollings Cancer Center at Medical University of South Carolina, Charleston

30322

Emory University Hospital - Atlanta, Atlanta

32207

Nemours Children's Clinic, Jacksonville

33136

University of Miami Sylvester Comprehensive Cancer Center, Miami

33155

Miami Children's Hospital, Miami

33407

Kaplan Cancer Center at St. Mary's Medical Center, West Palm Beach

33607

St. Joseph's Cancer Institute at St. Joseph's Hospital, Tampa

33701

All Children's Hospital, St. Petersburg

35294

Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham

38105

St. Jude Children's Research Hospital, Memphis

40232

Kosair Children's Hospital, Louisville

46260

St. Vincent Indianapolis Hospital, Indianapolis

48236

Van Elslander Cancer Center at St. John Hospital and Medical Center, Grosse Pointe Woods

48503

Hurley Medical Center, Flint

53226

Midwest Children's Cancer Center, Milwaukee

54449

Marshfield Clinic - Marshfield Center, Marshfield

55404

Children's Hospital of Minnesota - Minneapolis, Minneapolis

55455

Fairview University Medical Center - University Campus, Minneapolis

55905

Mayo Clinic Cancer Center, Rochester

60614

Children's Memorial Hospital - Chicago, Chicago

64108

Children's Mercy Hospital, Kansas City

70118

Children's Hospital of New Orleans, New Orleans

72205

Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock

75390

Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas

76508

CCOP - Scott and White Hospital, Temple

79106

Texas Tech University Health Sciences Center School of Medicine, Amarillo

79410

Covenant Children's Hospital, Lubbock

92868

Children's Hospital of Orange County, Orange

95825

Kaiser Permanente Medical Center - Oakland, Sacramento

85016-7710

Phoenix Children's Hospital, Phoenix

90095-1781

Jonsson Comprehensive Cancer Center at UCLA, Los Angeles

94609-1809

Children's Hospital and Research Center - Oakland, Oakland

20010-2970

Children's National Medical Center, Washington D.C.

32610-0232

University of Florida Shands Cancer Center, Gainesville

62794-9620

Southern Illinois University School of Medicine, Springfield

46202-5289

Indiana University Cancer Center, Indianapolis

66160-7357

Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center, Kansas City

21231-2410

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore

02114

Massachusetts General Hospital Cancer Center, Boston

48109-0238

C.S. Mott Children's Hospital at University of Michigan, Ann Arbor

48201-1379

Barbara Ann Karmanos Cancer Institute, Detroit

49503-2560

Spectrum Health Cancer Care - Butterworth Campus, Grand Rapids

39216-4505

University of Mississippi Medical Center, Jackson

07601

Hackensack University Medical Center Cancer Center, Hackensack

14263-0001

Roswell Park Cancer Institute, Buffalo

11794-8174

Long Island Cancer Center at Stony Brook University Hospital, Stony Brook

45229-3039

Cincinnati Children's Hospital Medical Center, Cincinnati

44106-5000

Rainbow Babies and Children's Hospital, Cleveland

45404-1815

Children's Medical Center - Dayton, Dayton

17033-0850

Penn State Cancer Institute at Milton S. Hershey Medical Center, Hershey

76104-9958

Cook Children's Medical Center - Fort Worth, Fort Worth

78229-3900

University of Texas Health Science Center at San Antonio, San Antonio

78229-3993

Methodist Children's Hospital of South Texas, San Antonio

23507-1971

Children's Hospital of the King's Daughters, Norfolk

54307-3508

St. Vincent Hospital Regional Cancer Center, Green Bay

H3T 1C5

Hopital Sainte Justine, Montreal

S7N 4H4

Saskatoon Cancer Centre at the University of Saskatchewan, Saskatoon

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK

NCT00070187 - Immunotherapy Using Cyclosporine, Interferon Gamma, and Interleukin-2 After High-Dose Myeloablative Chemotherapy With Autologous Stem Cell Transplantation in Treating Patients With Refractory or Relapsed Hodgkin's Lymphoma | Biotech Hunter | Biotech Hunter