Gemtuzumab Ozogamicin in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia Undergoing Remission Induction and Intensification Therapy

PHASE2CompletedINTERVENTIONAL
Enrollment

350

Participants

Timeline

Start Date

December 31, 2003

Primary Completion Date

September 30, 2006

Study Completion Date

December 31, 2013

Conditions
Leukemia
Interventions
DRUG

asparaginase

DRUG

busulfan

DRUG

cyclophosphamide

DRUG

cyclosporine

DRUG

cytarabine

DRUG

daunorubicin hydrochloride

DRUG

etoposide

DRUG

gemtuzumab ozogamicin

DRUG

methotrexate

DRUG

mitoxantrone hydrochloride

PROCEDURE

allogeneic bone marrow transplantation

Trial Locations (148)

2145

Westmead Hospital, Westmead

3010

Swiss Pediatric Oncology Group Bern, Bern

4029

Office of S. David Lang, Herston, Brisbane

6001

Princess Margaret Hospital for Children, Perth

10467

Albert Einstein Cancer Center at Albert Einstein College of Medicine, The Bronx

10595

New York Medical College, Valhalla

11040

Schneider Children's Hospital, New Hyde Park

11219

Maimonides Medical Center, Brooklyn

11501

Winthrop University Hospital, Mineola

13210

SUNY Upstate Medical University Hospital, Syracuse

14263

Roswell Park Cancer Institute, Buffalo

19134

St. Christopher's Hospital for Children, Philadelphia

19899

Alfred I. duPont Hospital for Children, Wilmington

21215

Alvin and Lois Lapidus Cancer Institute at Sinai Hospital, Baltimore

22031

INOVA Fairfax Hospital, Fairfax

24029

Carilion Cancer Center of Western Virginia, Roanoke

25302

West Virginia University - Robert C. Byrd Health Sciences Center - Charleston Division, Charleston

25701

Cabell Huntington Hospital, Huntington

27834

Leo W. Jenkins Cancer Center at Pitt County Memorial Hospital, Greenville

28232

Blumenthal Cancer Center at Carolinas Medical Center, Charlotte

28233

Presbyterian Cancer Center at Presbyterian Hospital, Charlotte

29425

Hollings Cancer Center at Medical University of South Carolina, Charleston

30322

Emory University Hospital - Atlanta, Atlanta

32207

Nemours Children's Clinic, Jacksonville

32504

Sacred Heart Cancer Center at Sacred Heart Hospital, Pensacola

32610

University of Florida Shands Cancer Center, Gainesville

32804

Florida Hospital Cancer Institute at Florida Hospital Orlando, Orlando

32806

M.D. Anderson Cancer Center - Orlando, Orlando

33021

Memorial Cancer Institute at Memorial Regional Hospital, Hollywood

33101

University of Miami Sylvester Comprehensive Cancer Center, Miami

33155

Miami Children's Hospital, Miami

33176

Baptist-South Miami Regional Cancer Program, Miami

33316

Broward General Medical Center Cancer Center, Fort Lauderdale

33407

Kaplan Cancer Center at St. Mary's Medical Center, West Palm Beach

33607

St. Joseph's Cancer Institute at St. Joseph's Hospital, Tampa

33701

All Children's Hospital, St. Petersburg

33908

Lee Cancer Care of Lee Memorial Health System, Fort Myers

35294

Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham

40506

Markey Cancer Center at University of Kentucky Chandler Medical Center, Lexington

43606

Toledo Hospital, Toledo

43608

Medical College of Ohio Cancer Institute, Toledo

46260

St. Vincent Indianapolis Hospital, Indianapolis

48201

Barbara Ann Karmanos Cancer Institute, Detroit

48236

Van Elslander Cancer Center at St. John Hospital and Medical Center, Grosse Point Woods

53226

Midwest Children's Cancer Center, Milwaukee

54301

St. Vincent Hospital, Green Bay

55404

Children's Hospitals and Clinics - Minneapolis/St. Paul, Minneapolis

58122

CCOP - MeritCare Hospital, Fargo

60614

Children's Memorial Hospital - Chicago, Chicago

63104

Cardinal Glennon Children's Hospital, St Louis

63110

Siteman Cancer Center at Barnes-Jewish Hospital, St Louis

64108

Children's Mercy Hospital, Kansas City

67214

Via Christi Cancer Center at Via Christi Regional Medical Center, Wichita

Wesley Medical Center, Wichita

72205

Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock

73104

Oklahoma University Medical Center, Oklahoma City

76508

CCOP - Scott and White Hospital, Temple

78207

University of Texas Health Science Center at San Antonio, San Antonio

78701

Children's Hospital of Austin, Austin

79106

Texas Tech University Health Sciences Center School of Medicine, Amarillo

79410

Covenant Children's Hospital, Lubbock

90027

Children's Hospital Los Angeles, Los Angeles

90801

Jonathan Jaques Children's Cancer Center at Miller Children's Hospital, Long Beach

92668

Children's Hospital of Orange County, Orange

95813

Cancer Research Center of Hawaii, Honolulu

95817

University of California Davis Cancer Center, Sacramento

95819

Sutter Cancer Center, Sacramento

95825

Kaiser Permanente Medical Center - Oakland, Sacramento

98105

Children's Hospital and Regional Medical Center - Seattle, Seattle

98405

Mary Bridge Children's Hospital and Health Center - Tacoma, Tacoma

98431

Madigan Army Medical Center, Tacoma

85016-7710

Phoenix Children's Hospital, Phoenix

90242-2814

Southern California Permanente Medical Group, Downey

92354-2870

Loma Linda University Cancer Institute at Loma Linda University Medical Center, Loma Linda

90048-1865

Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, Los Angeles

93638-8762

Children's Hospital Central California, Madera

94609-1809

Children's Hospital and Research Center - Oakland, Oakland

92123-4282

Children's Hospital and Health Center - San Diego, San Diego

80218-1088

Children's Hospital Cancer Center, Denver

06106

Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center, Hartford

20007-2197

Lombardi Cancer Center at Georgetown University Medical Center, Washington D.C.

20010-2970

Children's National Medical Center, Washington D.C.

31404-6283

Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center, Savannah

83712-6297

St. Luke's Mountain States Tumor Institute - Boise, Boise

60637-1463

University of Chicago Cancer Research Center, Chicago

60068-1174

Lutheran General Cancer Care Center, Park Ridge

62794-9230

Southern Illinois University School of Medicine, Springfield

46202-5225

Indiana University Cancer Center, Indianapolis

52242-1083

Holden Comprehensive Cancer Center at University of Iowa, Iowa City

40202-1822

Kosair Children's Hospital, Louisville

04401

CancerCare of Maine at Eastern Maine Medial Center, Bangor

04074-9308

Maine Children's Cancer Program, Scarborough

21287-5001

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore

02111

Floating Hospital for Children, Boston

48109-0238

C.S. Mott Children's Hospital at University of Michigan, Ann Arbor

48824-1313

Breslin Cancer Center at Ingham Regional Medical Center, East Lansing

49503-2560

Spectrum Health Cancer Care - Butterworth Campus, Grand Rapids

49007-5341

CCOP - Kalamazoo, Kalamazoo

55455-0392

Fairview University Medical Center - University Campus, Minneapolis

55905-0001

Mayo Clinic Cancer Center, Rochester

39216-4505

University of Mississippi Medical Center, Jackson

39534-2511

Keesler Medical Center - Keesler Air Force Base, Keesler Air Force Base

68114-4113

Children's Hospital of Omaha, Omaha

89109-2306

Sunrise Hospital and Medical Center, Las Vegas

07601

Hackensack University Medical Center, Hackensack

07039

St. Barnabas Medical Center, Livingston

08901

Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School, New Brunswick

07112-2094

Newark Beth Israel Medical Center, Newark

07503

St. Joseph's Hospital and Medical Center, Paterson

87131-0001

University of New Mexico Cancer Research and Treatment Center, Albuquerque

11201-5493

Brooklyn Hospital Center, Brooklyn

10032-1537

Herbert Irving Comprehensive Cancer Center at Columbia University, New York

28801-4690

Mission Hospitals - Memorial Campus, Asheville

27599-7220

Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill

27157-1081

Comprehensive Cancer Center at Wake Forest University, Winston-Salem

44308-1062

Children's Hospital Medical Center of Akron, Akron

45229-3039

Cincinnati Children's Hospital Medical Center, Cincinnati

44106-5000

Rainbow Babies and Children's Hospital, Cleveland

44195-5217

Cleveland Clinic Taussig Cancer Center, Cleveland

43205-2696

Columbus Children's Hospital, Columbus

45404-1815

Children's Medical Center - Dayton, Dayton

97201-3098

Cancer Institute at Oregon Health and Science University, Portland

17822-1320

Geisinger Medical Center, Danville

17033-0850

Penn State Cancer Institute at Milton S. Hershey Medical Center, Hershey

19104-9786

Children's Hospital of Philadelphia, Philadelphia

15213-2583

Children's Hospital of Pittsburgh, Pittsburgh

29203-6897

Palmetto Health South Carolina Cancer Center, Columbia

57117-5039

Sioux Valley Hospital and University of South Dakota Medical Center, Sioux Falls

37232-6310

Vanderbilt-Ingram Cancer Center, Nashville

78411-1721

Driscoll Children's Hospital, Corpus Christi

75390-9063

Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas

78229-3993

Methodist Children's Hospital of South Texas, San Antonio

84113-1100

Primary Children's Medical Center, Salt Lake City

05405

Fletcher Allen Health Care - University Health Center Campus, Burlington

23298-0121

Massey Cancer Center at Virginia Commonwealth University, Richmond

99220-2555

Providence Cancer Center at Sacred Heart Medical Center, Spokane

54601-5429

Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center, La Crosse

53792-0001

University of Wisconsin Comprehensive Cancer Center, Madison

T2T 5C7

Alberta Children's Hospital, Calgary

V6H 3V4

Children's & Women's Hospital of British Columbia, Vancouver

R3E 0V9

CancerCare Manitoba, Winnipeg

A1B 3V6

Janeway Children's Health and Rehabilitation Centre, St. John's

B3K 6R8

IWK Health Centre, Halifax

L8N 3Z5

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton

H3H 1P3

McGill Cancer Centre at McGill University, Montreal

H3T 1C5

Hopital Sainte Justine, Montreal

G1V 4G2

Centre Hospitalier Universitaire de Quebec, Ste-Foy

00912

San Jorge Children's Hospital, Santurce

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK

NCT00070174 - Gemtuzumab Ozogamicin in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia Undergoing Remission Induction and Intensification Therapy | Biotech Hunter | Biotech Hunter