96
Participants
Start Date
September 18, 2003
Primary Completion Date
March 16, 2005
Study Completion Date
March 16, 2005
Iduronate-2-sulfatase enzyme replacement therapy
Patients will receive weekly infusions of idursulfase at a dose of 0.5 mg/kg.
iduronate-2-sulfatase enzyme replacement therapy
Patients will receive every other week infusions of idursulfase at a dose of 0.5 mg/kg.
Placebo
Patients will receive weekly infusions of placebo.
University of North Carolina at Chapel Hill, Chapel Hill
St. Louis Children's Hospital, Washington University, St Louis
Texas Children's Hospital, Baylor College of Medicine, Houston
Children's Hospital Oakland, Oakland
Hospital de Clinicas de Porto Alegre, Porto Alegre
Children's Hospital, Johannes-Gutenburg Universitaet Mainz, Mainz
Addenbrooke's Hospital, Cambridge
Great Ormond Street Hospital for Sick Children, London
Royal Manchester Children's Hospital, Manchester
Lead Sponsor
Shire
INDUSTRY