10
Participants
Start Date
June 30, 2003
Primary Completion Date
March 31, 2004
anti-thymocyte globulin
anti-thymocyte globulin IV over 4 hours on days -2 to -1
cyclophosphamide
cyclophosphamide IV over 1 hour on days -3 to -2
cyclosporine
oral cyclosporine on days -1 to 100
fludarabine phosphate
fludarabine IV over 30 minutes on days -8 to -4
methylprednisolone
methylprednisolone (oral or IV) on days 5-15
UV light therapy
Patients undergo ultraviolet-B (UVB) light therapy every other day between days -10 and -2 for a total of 3 days. Posttransplantation UVB light therapy: Following PBSC transplantation, patients undergo UVB light therapy twice weekly on week 1 (at least 1 day apart) and three times weekly on weeks 2-4.
allogeneic bone marrow transplantation
peripheral blood stem cell transplantation
Allogeneic peripheral blood stem cell (PBSC) transplantation: Patients undergo PBSC transplantation on day 0.
Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center, Cleveland
Case Comprehensive Cancer Center
OTHER