39
Participants
Start Date
February 24, 2004
Primary Completion Date
June 30, 2009
Study Completion Date
May 31, 2011
Doxorubicin
Doxorubicin: 50 mg/m² IV slow push followed by gemcitabine 1500 mg/m² IV infusion over 30 minutes on day 1. Cycles repeat every 2 weeks.
Gemcitabine
Doxorubicin: 50 mg/m² IV slow push followed by gemcitabine 1500 mg/m² IV infusion over 30 minutes on day 1. Cycles repeat every 2 weeks.
G-CSF (granulocyte-colony stimulating factor)
Patients will receive G-CSF at a subcutaneous dose of 5mcg/kg/day on days 2 or 3 to 10 or neulasta at a dose of 6mg on day 2. Growth factor must be administered as close as possible to 24 hours after the completion of chemotherapy. It is recommended that neulasta be administered only on day 2 due to its prolonged half-life.
Neulasta
Patients will receive G-CSF at a subcutaneous dose of 5mcg/kg/day on days 2 or 3 to 10 or neulasta at a dose of 6mg on day 2. Growth factor must be administered as close as possible to 24 hours after the completion of chemotherapy. It is recommended that neulasta be administered only on day 2 due to its prolonged half-life.
Our Lady of Mercy Medical Center Comprehensive Cancer Center, The Bronx
CCOP - Hematology-Oncology Associates of Central New York, Syracuse
Mount Nittany Medical Center, State College
Central Pennsylvania Hematology and Medical Oncology Associates, PC, Lemoyne
Lewistown Hospital, Lewistown
Community Comprehensive Cancer Center at Camden-Clark Memorial Hospital, Parkersburg
St. Rita's Medical Center, Lima
William N. Wishard Memorial Hospital, Indianapolis
Center for Cancer Therapy at LaPorte Hospital and Health Services, La Porte
Saint Anthony Memorial Health Centers, Michigan City
Elkhart General Hospital, Elkhart
CCOP - Northern Indiana CR Consortium, South Bend
Memorial Hospital of South Bend, South Bend
Saint Joseph Regional Medical Center, South Bend
Howard Community Hospital at Howard Regional Health System, Kokomo
St. John Macomb Hospital, Warren
CCOP - Michigan Cancer Research Consortium, Ann Arbor
Van Elslander Cancer Center at St. John Hospital and Medical Center, Grosse Pointe Woods
Genesys Hurley Cancer Institute, Flint
Hurley Medical Center, Flint
Seton Cancer Institute - Saginaw, Saginaw
Sparrow Regional Cancer Center, Lansing
Borgess Medical Center, Kalamazoo
Bronson Methodist Hospital, Kalamazoo
Lakeland Cancer Care Center at Lakeland Hospital - St. Joseph, Saint Joseph
Foote Hospital, Jackson
McFarland Clinic, PC, Ames
Siouxland Hematology-Oncology Associates, LLP, Sioux City
Siouxland Regional Cancer Center, Sioux City
St. Luke's Regional Medical Center, Sioux City
Cedar Rapids Oncology Associates, Cedar Rapids
Medical Consultants, Limited, Milwaukee
Marshfield Clinic - Marshfield Center, Marshfield
Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center, La Crosse
Marshfield Clinic - Indianhead Center, Rice Lake
CCOP - Duluth, Duluth
Miller-Dwan Medical Center, Duluth
St. Mary's - Duluth Clinic Cancer Center, Duluth
Mayo Clinic Cancer Center, Rochester
Avera Cancer Institute, Sioux Falls
Medical X-Ray Center, PC, Sioux Falls
CCOP - Montana Cancer Consortium, Billings
Hematology-Oncology Centers of the Northern Rockies - Billings, Billings
Northern Rockies Radiation Oncology Center, Billings
St. Vincent Healthcare, Billings
Great Falls Clinic, Great Falls
Great Falls
St. Peter's Hospital, Helena
St. James Community Hospital, Butte
Bozeman Deaconess Cancer Center, Bozeman
Community Medical Center, Missoula
Guardian Oncology and Center for Wellness, Missoula
Montana Cancer Center at St. Patrick Hospital and Health Sciences Center, Missoula
Glacier Oncology, PLLC, Kalispell
Kalispell Medical Oncology, Kalispell
Kalispell Regional Medical Center, Kalispell
North Shore Oncology and Hematology Associates, Limited - Libertyville, Libertyville
Hematology Oncology Associates - Skokie, Skokie
Hematology/Oncology of the North Shore at Gross Point Medical Center, Skokie
Midwest Center for Hematology/Oncology, Joliet
Joliet Oncology-Hematology Associates, Limited - West, Joliet
Rush-Copley Cancer Care Center, Aurora
Hematology and Oncology Associates, Chicago
Veterans Affairs Medical Center - Lakeside Chicago, Chicago
Mercy Hospital and Medical Center, Chicago
Cancer Care and Hematology Specialists of Chicagoland - Niles, Niles
Carle Cancer Center at Carle Foundation Hospital, Urbana
CCOP - Carle Cancer Center, Urbana
University of Colorado Cancer Center at UC Health Sciences Center, Aurora
Welch Cancer Center at Sheridan Memorial Hospital, Sheridan
USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles
Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago
University of Chicago Cancer Research Center, Chicago
Indiana University Cancer Center, Indianapolis
Cancer Research Center at Boston Medical Center, Boston
Beth Israel Deaconess Medical Center, Boston
Saint Joseph Mercy Cancer Center, Ann Arbor
Oakwood Cancer Center at Oakwood Hospital and Medical Center, Dearborn
Barbara Ann Karmanos Cancer Institute, Detroit
West Michigan Cancer Center, Kalamazoo
Billings Clinic Cancer Center, Billings
Deaconess Billings Clinic - Downtown, Billings
Montana Cancer Specialists at Montana Cancer Center, Missoula
Hunterdon Regional Cancer Center at Hunterdon Medical Center, Flemington
CCOP - Northern New Jersey, Hackensack
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School, New Brunswick
Roswell Park Cancer Institute, Buffalo
Penn State Cancer Institute at Milton S. Hershey Medical Center, Hershey
Fox Chase Cancer Center - Philadelphia, Philadelphia
Sioux Valley Hospital and University of South Dakota Medical Center, Sioux Falls
University of Wisconsin Paul P. Carbone Comprehensive Cancer Center, Madison
Aurora Sinai Medical Center, Milwaukee
National Cancer Institute (NCI)
NIH
Eastern Cooperative Oncology Group
NETWORK