150
Participants
Start Date
August 31, 2003
Primary Completion Date
June 30, 2008
Study Completion Date
June 30, 2008
Ultrafiltration
All patients participating in the trial require evaluation of dry-weight at each dialysis visit for evaluation. An initial weight loss of 0.1kg/10 kg body-weight will be prescribed per dialysis. If ultrafiltration is not tolerated based on muscle cramps, need for excessive saline or symptomatic hypotension, the intensity of ultrafiltration will be reduced by 50%. If ultrafiltration is still not tolerated, the weight loss will be further reduced by 50%. If the patient cannot tolerate at least 0.2 kg incremental weight loss per dialysis, the patient will be said to be at goal dry-weight. Thus, by this protocol, all patients must experience symptoms of volume depletion to be at dry weight.
Indiana University Affiliated Dialysis Unit, Indianapolis
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Indiana University
OTHER