Hypertension in Hemodialysis

NACompletedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

August 31, 2003

Primary Completion Date

June 30, 2008

Study Completion Date

June 30, 2008

Conditions
HypertensionLeft Ventricular Hypertrophy
Interventions
OTHER

Ultrafiltration

All patients participating in the trial require evaluation of dry-weight at each dialysis visit for evaluation. An initial weight loss of 0.1kg/10 kg body-weight will be prescribed per dialysis. If ultrafiltration is not tolerated based on muscle cramps, need for excessive saline or symptomatic hypotension, the intensity of ultrafiltration will be reduced by 50%. If ultrafiltration is still not tolerated, the weight loss will be further reduced by 50%. If the patient cannot tolerate at least 0.2 kg incremental weight loss per dialysis, the patient will be said to be at goal dry-weight. Thus, by this protocol, all patients must experience symptoms of volume depletion to be at dry weight.

Trial Locations (1)

46202

Indiana University Affiliated Dialysis Unit, Indianapolis

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

Indiana University

OTHER

NCT00067665 - Hypertension in Hemodialysis | Biotech Hunter | Biotech Hunter