140
Participants
Start Date
November 30, 2002
Primary Completion Date
June 30, 2008
Study Completion Date
July 31, 2008
Nortriptyline Oral Capsule
Nortriptyline will be titrated up from 25 mg qhs to a maximum dose of 150 mg qhs based on treatment response and side effect profile.
Benztropine Oral Product
Benztropine will be titrated up from .125 mg qhs to a maximum dose of .750 mg qhs based on treatment response and side effect profile.
CBT
Six in-person, individual sessions of cognitive-behavioral therapy for pain management include relaxation training, pain coping skills training, cognitive therapy for negative and dysfunctional thoughts, and diaries for monitoring relaxation, goals, and negative thinking.
Disease MGT
Six in-person, individual sessions of temporomandibular joint disorder (TMD) disease management (MGT) that include information about the jaw and good oral habits, diet, sleep, and general stress management.
University of Maryland, Dental School, Baltimore
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Johns Hopkins University
OTHER