Sertraline Compared With Hypericum Perforatum (St.John's Wort) in Treating Depression

PHASE3CompletedINTERVENTIONAL
Enrollment

2

Participants

Timeline

Start Date

March 1, 2004

Primary Completion Date

April 1, 2005

Study Completion Date

November 1, 2005

Conditions
DepressionUnspecified Adult Solid Tumor, Protocol Specific
Interventions
DRUG

Zoloft 50 mg

Zoloft 50 mg by mouth daily for 1 week if tolerated dose may be increased to 100 mg daily for 4 months

DIETARY_SUPPLEMENT

St. John's Wort 600 mg

St. John's wort 600 mg daily for 1 week, if tolerated. Dose may be increased to 900 mg daily for 4 months.

Trial Locations (6)

27261

High Point Regional Hospital, High Point

30165

Regional Radiation Oncology Center at Rome, Rome

62526

CCOP - Central Illinois, Decatur

94609-3305

Bay Area Tumor Institute, Oakland

27534-9479

CCOP - Southeast Cancer Control Consortium, Goldsboro

27157-1082

Comprehensive Cancer Center at Wake Forest University, Winston-Salem

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Wake Forest University Health Sciences

OTHER

NCT00066859 - Sertraline Compared With Hypericum Perforatum (St.John's Wort) in Treating Depression | Biotech Hunter | Biotech Hunter